Human PWWP3A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PWWP3A
Locus ID	84939
Kit Components	GA113784G1, PWWP3A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113784G2, PWWP3A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113784G3, PWWP3A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_032853, NR_024247, NM_001369791, NM_001369796, NM_001369797, NM_001369789, NM_001369790, NM_001369792, NM_001369793, NM_001369794, NM_001369795, NR_163148, NR_163149
Synonyms	EXPAND1; HSPC211; MUM-1
Summary	Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.[UniProtKB/Swiss-Prot Function]

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