Human WDR85 (DPH7) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DPH7
Locus ID	92715
Kit Components	GA114235G1, WDR85 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114235G2, WDR85 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114235G3, WDR85 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_138778, NM_001346370, NM_001346371, NM_001346372, NM_001346373, NM_001346374, NM_001346375, NM_001346376, NM_001346377, NM_001346378, NM_001346379, NM_001346380, NM_001346381, NM_001346382, NM_001346383, NM_001346384, NM_001346385, NM_001346386, NM_001346387, NM_001346388, NM_001346389, NM_001346390, NM_001346391, NM_001346392, NM_001346393, NM_001346394, NM_001346395, NM_001346396
Synonyms	C9orf112; RRT2; WDR85
Summary	Diphthamide is a post-translationally modified histidine residue present in elongation factor 2, and is the target of diphtheria toxin. This gene encodes a protein that contains a WD-40 domain, and is thought to be involved in diphthamide biosynthesis. A similar protein in yeast functions as a methylesterase, converting methylated diphthine to diphthine, which can then undergo amidation to produce diphthamide. [provided by RefSeq, Oct 2016]

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