Human EXOSC6 activation kit by CRISPRa

CAT#: GA114660

EXOSC6 CRISPRa kit - CRISPR gene activation of human exosome component 6



  See Other Versions

CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
Rabbit Polyclonal Anti-EXOSC6 Antibody
    • 100 ul

CNY 5,250.00


EXOSC6 (Myc-DDK-tagged)-Human exosome component 6 (EXOSC6)
    • 10 ug

CNY 2,400.00
CNY 3,990.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol EXOSC6
Locus ID 118460
Kit Components

GA114660G1, EXOSC6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114660G2, EXOSC6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114660G3, EXOSC6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_058219
Synonyms EAP4; hMtr3p; MTR3; Mtr3p; p11
Summary This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Other Versions

Customer Reviews 
Loading...