Human DRAM2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DRAM2
Locus ID	128338
Kit Components	GA115034G1, DRAM2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115034G2, DRAM2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115034G3, DRAM2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_178454, NM_001349881, NM_001349882, NM_001349884, NM_001349885, NM_001349886, NM_001349887, NM_001349888, NM_001349889, NM_001349890, NM_001349891, NM_001349892, NM_001349893, NR_146301, NR_146302, NR_146303, NR_146304, NR_146305, NR_146306, NR_146307, NR_146308
Synonyms	CORD21; PRO180; TMEM77; WWFQ154
Summary	The protein encoded by this gene binds microtubule-associated protein 1 light chain 3 and is required for autophagy. Defects in this gene are a cause of retinal dystrophy. In addition, two microRNAs (microRNA 125b-1 and microRNA 144) can bind to the mRNA of this gene and produce the disease state. [provided by RefSeq, Mar 2017]

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