Human IL17RE activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IL17RE
Locus ID	132014
Kit Components	GA115162G1, IL17RE gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115162G2, IL17RE gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115162G3, IL17RE gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001193380, NM_144640, NM_153480, NM_153481, NM_153482, NM_153483, NR_104198
Synonyms	FLJ23658; MGC71884
Summary	This gene encodes a transmembrane protein that functions as the receptor for interleukin-17C. The encoded protein signals to downstream components of the mitogen activated protein kinase (MAPK) pathway. Activity of this protein is important in the immune response to bacterial pathogens. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013]

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