Human PARIS (ZNF746) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZNF746
Locus ID	155061
Kit Components	GA115909G1, PARIS gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115909G2, PARIS gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115909G3, PARIS gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001163474, NM_152557, NM_001363517
Synonyms	PARIS
Summary	Transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death.[UniProtKB/Swiss-Prot Function]

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