Human GARNL1 (RALGAPA1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RALGAPA1
Locus ID	253959
Kit Components	GA116762G1, GARNL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116762G2, GARNL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116762G3, GARNL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001283043, NM_001283044, NM_001330075, NM_001346243, NM_001346245, NM_001346246, NM_001346247, NM_001346248, NM_001346249, NM_014990, NM_194301
Synonyms	GARNL1; GRIPE; p240; RalGAPalpha1; TULIP1
Summary	This gene encodes a major subunit of the RAL-GTPase activating protein. A similar protein in mouse binds E12, a transcriptional regulator of immunoglobulin genes. The mouse protein also functions in skeletal muscle by binding to the regulatory 14-3-3 proteins upon stimulation with insulin or muscle contraction. A pseudogene of this gene has been identified on chromosome 9. [provided by RefSeq, Oct 2016]

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