Human Tetraspanin 33 (TSPAN33) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TSPAN33
Locus ID	340348
Kit Components	GA117472G1, Tetraspanin 33 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117472G2, Tetraspanin 33 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117472G3, Tetraspanin 33 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_178562
Synonyms	PEN; PEN.; TSPAN-33
Summary	Plays an important role in normal erythropoiesis (By similarity). It has a role in the differentiation of erythroid progenitors (By similarity). Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:26686862). Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity (PubMed:26686862).[UniProtKB/Swiss-Prot Function]

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