Mouse Grm8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Grm8
Locus ID	14823
Kit Components	GA201747G1, Grm8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201747G2, Grm8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201747G3, Grm8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001311072, NM_008174, NM_001361125
Synonyms	A230002O04; Gprc1h; mGluR8
Summary	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.[UniProtKB/Swiss-Prot Function]

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