Mouse H2-Ke6 activation kit by CRISPRa
CAT#: GA201811
H2-Ke6 CRISPRa kit - CRISPR gene activation of mouse H2-K region expressed gene 6
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | H2-Ke6 |
Locus ID | 14979 |
Kit Components | GA201811G1, H2-Ke6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201811G2, H2-Ke6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201811G3, H2-Ke6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_013543 |
Synonyms | D17H6S112E; H-2Ke6; Hsd17b8; Ke-6; Ke6; Ring2 |
Summary | NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone (PubMed:9712896). The heterotetramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN507520 | H2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |