Mouse Foxj1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Foxj1
Locus ID	15223
Kit Components	GA201887G1, Foxj1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201887G2, Foxj1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201887G3, Foxj1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_008240
Synonyms	FKHL-13; HFH-4; Hfh4
Summary	Transcription factor specifically required for the formation of motile cilia (PubMed:9096351, PubMed:9739041, PubMed:10873152, PubMed:14996907, PubMed:22357932, PubMed:27965440). Acts by activating transcription of genes that mediate assembly of motile cilia, such as CFAP157 (PubMed:27965440). Binds the DNA consensus sequences 5'-HWDTGTTTGTTTA-3' or 5'-KTTTGTTGTTKTW-3' (where H is not G, W is A or T, D is not C, and K is G or T) (PubMed:9096351). Activates the transcription of a variety of ciliary proteins in the developing brain and lung (PubMed:28666954, PubMed:27914912).[UniProtKB/Swiss-Prot Function]

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