Mouse Irgm1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Irgm1
Locus ID	15944
Kit Components	GA202064G1, Irgm1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202064G2, Irgm1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202064G3, Irgm1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_008326, NM_001355757
Synonyms	Ifggd3; Ifi1; Iigp3; Iipg3; Irgm; LRG-47
Summary	Putative GTPase which is required for IFNG-mediated clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. Required for macrophage motility and possibly also for adhesion.[UniProtKB/Swiss-Prot Function]

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