Mouse Itm2b activation kit by CRISPRa
CAT#: GA202220
Itm2b CRISPRa kit - CRISPR gene activation of mouse integral membrane protein 2B
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Itm2b |
Locus ID | 16432 |
Kit Components | GA202220G1, Itm2b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202220G2, Itm2b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202220G3, Itm2b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_008410 |
Synonyms | AI256040; Bri; Bri2; Bricd2b; D14Sel6; E25BMM; imBRI2 |
Summary | Plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN508510 | Itm2b - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |