Mouse Pou4f3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pou4f3
Locus ID	18998
Kit Components	GA203334G1, Pou4f3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203334G2, Pou4f3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203334G3, Pou4f3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_138945
Synonyms	Brn3.1; Brn3c; ddl; dreidel
Summary	Acts as a transcriptional activator (PubMed:8290353, PubMed:7935408). Acts by binding to sequences related to the consensus octamer motif 5'-ATGCAAAT-3' in the regulatory regions of its target genes (PubMed:7935408). Involved in the auditory system development, required for terminal differentiation of hair cells in the inner ear (PubMed:8637595).[UniProtKB/Swiss-Prot Function]

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