Mouse Sag activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sag
Locus ID	20215
Kit Components	GA203758G1, Sag gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203758G2, Sag gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203758G3, Sag gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_009118
Synonyms	A930001K18Rik; Arr1; arrestin; Irbp
Summary	Binds to photoactivated, phosphorylated RHO and terminates RHO signaling via G-proteins by competing with G-proteins for the same binding site on RHO (PubMed:9333241, PubMed:16421323). May play a role in preventing light-dependent degeneration of retinal photoreceptor cells (PubMed:16421323).[UniProtKB/Swiss-Prot Function]

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