Mouse Sphk1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sphk1
Locus ID	20698
Kit Components	GA204049G1, Sphk1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204049G2, Sphk1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204049G3, Sphk1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001172472, NM_001172473, NM_001172475, NM_011451, NM_025367
Synonyms	1110006G24Rik; Sk1; Spk1
Summary	This gene encodes a kinase that phosphorylates sphingosine into sphingosine-1-phosphate, which is involved in cell differentiation, motility, and apoptosis. The encoded protein plays a role in maintaining cellular levels of sphingosine-1-phosphate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

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