Mouse Trim26 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Trim26
Locus ID	22670
Kit Components	GA204691G1, Trim26 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204691G2, Trim26 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204691G3, Trim26 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001025599, NM_001286726, NM_001286727, NM_030698
Synonyms	AI462198; Zfp173; Zfp1736
Summary	E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs). Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1.[UniProtKB/Swiss-Prot Function]

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