Mouse Lsm2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Lsm2
Locus ID	27756
Kit Components	GA205179G1, Lsm2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205179G2, Lsm2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205179G3, Lsm2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001110101, NM_001204273, NM_001204274, NM_030597
Synonyms	D17H6S56E-2; D17H6S56E2; Dmapl; Dmpkap; G7b; Sm-X5; SmX5; snRNP
Summary	Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.[UniProtKB/Swiss-Prot Function]

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