Mouse Rgs3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rgs3
Locus ID	50780
Kit Components	GA205360G1, Rgs3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205360G2, Rgs3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205360G3, Rgs3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001081650, NM_001310706, NM_019492, NM_134257
Synonyms	4930506N09Rik; C2pa; C2PA-RGS3; PDZ-RGS3; RGS3S
Summary	Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases.[UniProtKB/Swiss-Prot Function]

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