Mouse Cenpo activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cenpo
Locus ID	52504
Kit Components	GA205480G1, Cenpo gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205480G2, Cenpo gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205480G3, Cenpo gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_134046, NM_001361641
Synonyms	2810429O05Rik; 8430427C03Rik; D12Ertd482e
Summary	Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Modulates the kinetochore-bound levels of NDC80 complex (By similarity).[UniProtKB/Swiss-Prot Function]

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