Mouse Pla2g6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pla2g6
Locus ID	53357
Kit Components	GA205558G1, Pla2g6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205558G2, Pla2g6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205558G3, Pla2g6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001199023, NM_001199024, NM_001199025, NM_016915
Synonyms	BB112799; iPLA(2)beta; iPLA2; iPLA2beta; PNPLA9
Summary	Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods (By similarity).[UniProtKB/Swiss-Prot Function]

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