Mouse Atxn10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Atxn10
Locus ID	54138
Kit Components	GA205643G1, Atxn10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205643G2, Atxn10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205643G3, Atxn10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_016843
Synonyms	AI325283; C77170; E46; Sca10; TEG-169; Tex169
Summary	Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.[UniProtKB/Swiss-Prot Function]

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