Mouse St3gal6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	St3gal6
Locus ID	54613
Kit Components	GA205737G1, St3gal6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205737G2, St3gal6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205737G3, St3gal6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_018784, NM_001357433, NM_001357434, NM_001357435
Synonyms	1700023B24Rik; AI930218; AW552396; Siat10; St3galVI
Summary	Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1 (By similarity).[UniProtKB/Swiss-Prot Function]

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