Mouse Supt20 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Supt20
Locus ID	56790
Kit Components	GA206093G1, Supt20 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206093G2, Supt20 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206093G3, Supt20 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_019995, NM_001358015, NM_001358017, NR_152184, NR_152185, NR_152186
Synonyms	AA667204; AI450544; D3Ertd300e; Fam48a; p38IP; Supt20h
Summary	Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail. Required for starvation-induced ATG9A trafficking during autophagy.[UniProtKB/Swiss-Prot Function]

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