Mouse Gtf2ird1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gtf2ird1
Locus ID	57080
Kit Components	GA206126G1, Gtf2ird1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206126G2, Gtf2ird1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206126G3, Gtf2ird1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001081462, NM_001081463, NM_001081464, NM_001081465, NM_001081466, NM_001081467, NM_001081468, NM_001081469, NM_001081470, NM_001244936, NM_001347488, NM_020331
Synonyms	1700012P16Rik; BEN; Cream1; ESTM9; Gtf2il; GTF3; MusTRD1; Tg(Alb1-Myc)166.8Sst; WBSCR11; X83320
Summary	May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8.[UniProtKB/Swiss-Prot Function]

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