Mouse Akip1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Akip1
Locus ID	57373
Kit Components	GA206176G1, Akip1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206176G2, Akip1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206176G3, Akip1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_020616
Synonyms	BCA3; C11orf17; D7H11orf17; D930014E17Rik; ICRFP703B1614Q5.6; ORF27
Summary	Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade (By similarity).[UniProtKB/Swiss-Prot Function]

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