Mouse Il17re activation kit by CRISPRa
CAT#: GA206236
Il17re CRISPRa kit - CRISPR gene activation of mouse interleukin 17 receptor E
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Il17re |
Locus ID | 57890 |
Kit Components | GA206236G1, Il17re gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206236G2, Il17re gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206236G3, Il17re gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001034029, NM_001034031, NM_145826, NM_001362204, NM_001362205 |
Synonyms | AA589509; IL-17RE; Il25r |
Summary | Specific functional receptor for IL17C, signaling through the NF-kappa-B and MAPK pathways. Requires TRAF3IP2 /ACT1 for signaling. Crucial regulator in innate immunity to bacterial pathogens, such as Citrobacter rodentium. Isoform 4 and isoform 5 may be either cytoplasmic inactive or dominant active forms. Isoform 2 and isoform 3 may act as soluble decoy receptors.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN508243 | Il17re - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |