Mouse Erbin activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Erbin
Locus ID	59079
Kit Components	GA206364G1, Erbin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206364G2, Erbin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206364G3, Erbin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001005868, NM_001289473, NM_001289474, NM_001289475, NM_021563
Synonyms	1700028E05Rik; Erbb2ip; mKIAA1225
Summary	Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated ERBB2 'Tyr-1248' receptor, it may contribute to stabilize this unphosphorylated state (By similarity). Inhibits NOD2-dependent NF-kappa-B signaling and proinflammatory cytokine secretion (PubMed:16203728).[UniProtKB/Swiss-Prot Function]

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