Mouse Asb4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Asb4
Locus ID	65255
Kit Components	GA206523G1, Asb4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206523G2, Asb4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206523G3, Asb4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_023048, NM_001355662
Synonyms	8430401O13Rik; AV117194; AW060255
Summary	Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes differentiation and maturation of the vascular lineage by an oxygen-dependent mechanism.[UniProtKB/Swiss-Prot Function]

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