Mouse Slc30a7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc30a7
Locus ID	66500
Kit Components	GA206814G1, Slc30a7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206814G2, Slc30a7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206814G3, Slc30a7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_023214
Synonyms	1810059J10Rik; 2610034N15Rik; 4833428C12Rik; AI467242; ZnT-7; ZnT7; Zntl2
Summary	Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity).[UniProtKB/Swiss-Prot Function]

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