Mouse Fbxo25 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Fbxo25
Locus ID	66822
Kit Components	GA206973G1, Fbxo25 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206973G2, Fbxo25 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206973G3, Fbxo25 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001347316, NM_025785, NM_001359061
Synonyms	9130015I06Rik; AI649137; Fbx25
Summary	Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT).[UniProtKB/Swiss-Prot Function]

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