Mouse Socs4 activation kit by CRISPRa
CAT#: GA207249
Socs4 CRISPRa kit - CRISPR gene activation of mouse suppressor of cytokine signaling 4
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Socs4 |
Locus ID | 67296 |
Kit Components | GA207249G1, Socs4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207249G2, Socs4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207249G3, Socs4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_080843 |
Synonyms | 3110032M18Rik; A730004F22Rik; AI427843; AU015727; AU015859; Socs7 |
Summary | SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN516457 | Socs4 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |