Mouse Dock5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dock5
Locus ID	68813
Kit Components	GA207946G1, Dock5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207946G2, Dock5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207946G3, Dock5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_177780
Synonyms	1110060D06Rik; AI666732; AI956923; BC016533; E130320D18; lr2; rlc
Summary	Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP (PubMed:18396277). Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (By similarity).[UniProtKB/Swiss-Prot Function]

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