Mouse Arhgef12 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Arhgef12
Locus ID	69632
Kit Components	GA208252G1, Arhgef12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208252G2, Arhgef12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208252G3, Arhgef12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_027144, NM_001359232
Synonyms	2310014B11Rik; AU019857; Larg; mKIAA0382
Summary	May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13 (By similarity).[UniProtKB/Swiss-Prot Function]

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