Mouse Dctn2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dctn2
Locus ID	69654
Kit Components	GA208261G1, Dctn2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208261G2, Dctn2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208261G3, Dctn2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001190453, NM_001190454, NM_027151
Synonyms	2310042E05Rik; C87049; C130077D06Rik; DCTN-50; GMP23-48K; p50; RBP50
Summary	Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.[UniProtKB/Swiss-Prot Function]

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