Mouse Dcaf7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dcaf7
Locus ID	71833
Kit Components	GA208967G1, Dcaf7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208967G2, Dcaf7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208967G3, Dcaf7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_027946
Synonyms	1700012F10Rik; 2610037L01Rik; C86529; HAN11; Wdr68
Summary	Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches. Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity).[UniProtKB/Swiss-Prot Function]

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