Mouse Rnf6 activation kit by CRISPRa
CAT#: GA209735
Rnf6 CRISPRa kit - CRISPR gene activation of mouse ring finger protein (C3H2C3 type) 6
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Rnf6 |
Locus ID | 74132 |
Kit Components | GA209735G1, Rnf6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209735G2, Rnf6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209735G3, Rnf6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001256085, NM_001256086, NM_001256087, NM_028774 |
Synonyms | 1200013I08Rik; 5730419H05Rik; AA537053 |
Summary | E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN514959 | Rnf6 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |