Mouse Erp44 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Erp44
Locus ID	76299
Kit Components	GA210476G1, Erp44 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210476G2, Erp44 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210476G3, Erp44 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_029572, NM_001355184
Synonyms	1110001E24Rik; AI849526; AL033348; Txndc4
Summary	Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum (By similarity).[UniProtKB/Swiss-Prot Function]

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