Mouse Sdccag8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sdccag8
Locus ID	76816
Kit Components	GA210625G1, Sdccag8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210625G2, Sdccag8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210625G3, Sdccag8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_029756, NM_001357390, NR_151682
Synonyms	2700048G21Rik; 5730470G24Rik; Cccap
Summary	Plays a role in the establishment of cell polarity and epithelial lumen formation (PubMed:20835237). Plays also an essential role in ciliogenesis and subsequent Hedgehog signaling pathway that requires the presence of intact primary cilia for pathway activation. Mechanistically, interacts with and mediates RABEP2 centrosomal localization which is critical for ciliogenesis (PubMed:27224062).[UniProtKB/Swiss-Prot Function]

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