Mouse Dlst activation kit by CRISPRa

CAT#: GA211072

Dlst CRISPRa kit - CRISPR gene activation of mouse dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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经常一起买 (1)
DLST Antibody - middle region
    • 100 ul

CNY 5,250.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Dlst
Locus ID 78920
Kit Components

GA211072G1, Dlst gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA211072G2, Dlst gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA211072G3, Dlst gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_030225
Synonyms 1600017E01Rik; 4632413C10Rik; 4930529O08Rik; DLTS
Summary Dihydrolipoamide succinyltransferase (E2) component of the 2-oxoglutarate dehydrogenase complex (By similarity). The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) (By similarity). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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