Mouse Rbfox2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rbfox2
Locus ID	93686
Kit Components	GA211311G1, Rbfox2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211311G2, Rbfox2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211311G3, Rbfox2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001110827, NM_001110828, NM_001110829, NM_001110830, NM_001286417, NM_001286418, NM_001286419, NM_053104, NM_175387, NM_001358771, NM_001358772, NM_001358770
Synonyms	Fbm2; Fxh; Hrnbp2; Rbm9
Summary	RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. Seems to act as a coregulatory factor of ER-alpha (By similarity).[UniProtKB/Swiss-Prot Function]

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