Mouse Ppp1r8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ppp1r8
Locus ID	100336
Kit Components	GA211596G1, Ppp1r8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211596G2, Ppp1r8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211596G3, Ppp1r8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001290725, NM_146154, NM_001355198, NM_001355199
Synonyms	6330548N22Rik; AU044684; NIPP1
Summary	Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Essential for cell proliferation and early embryonic development.[UniProtKB/Swiss-Prot Function]

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