Mouse Chrnb3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Chrnb3
Locus ID	108043
Kit Components	GA212072G1, Chrnb3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212072G2, Chrnb3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212072G3, Chrnb3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_027454, NM_173212
Synonyms	5730417K16Rik; Acrb3
Summary	After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.[UniProtKB/Swiss-Prot Function]

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