Mouse Irak2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Irak2
Locus ID	108960
Kit Components	GA212170G1, Irak2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212170G2, Irak2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212170G3, Irak2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001113553, NM_172161
Synonyms	6330415L08Rik; AI649099; IRAK-2
Summary	Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.[UniProtKB/Swiss-Prot Function]

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