Mouse Tirap activation kit by CRISPRa
CAT#: GA212475
Tirap CRISPRa kit - CRISPR gene activation of mouse toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Tirap |
Locus ID | 117149 |
Kit Components | GA212475G1, Tirap gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212475G2, Tirap gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212475G3, Tirap gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001177845, NM_001177846, NM_001177847, NM_054096 |
Synonyms | AA407980; C130027E04Rik; Mal; Tlr4ap; Wyatt |
Summary | Adapter involved in the TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response (By similarity). Positively regulates the production of TNF-alpha and interleukin-6 (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN517596 | Tirap - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |