Mouse Shkbp1 activation kit by CRISPRa

CAT#: GA212705

Shkbp1 CRISPRa kit - CRISPR gene activation of mouse Sh3kbp1 binding protein 1



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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经常一起买 (1)
Shkbp1 Antibody - N-terminal region
    • 100 ul

CNY 5,250.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Shkbp1
Locus ID 192192
Kit Components

GA212705G1, Shkbp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA212705G2, Shkbp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA212705G3, Shkbp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_138676
Synonyms B930062H15Rik; Sb1
Summary Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation (PubMed:21830225).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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