Mouse Bcas3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Bcas3
Locus ID	192197
Kit Components	GA212710G1, Bcas3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212710G2, Bcas3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212710G3, Bcas3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001166642, NM_001166643, NM_138681
Synonyms	1500019F07Rik; 2610028P08Rik; AU021018; BC028339; K20D4; rudhira
Summary	Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin (By similarity). Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation.[UniProtKB/Swiss-Prot Function]

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