Mouse Ssh1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ssh1
Locus ID	231637
Kit Components	GA214276G1, Ssh1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214276G2, Ssh1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214276G3, Ssh1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_198109, NM_001363469
Synonyms	AW551225; Gm1394; Gm1395; SSH-1
Summary	Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.[UniProtKB/Swiss-Prot Function]

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