Mouse Scn3b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Scn3b
Locus ID	235281
Kit Components	GA214608G1, Scn3b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214608G2, Scn3b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214608G3, Scn3b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001083917, NM_001286614, NM_153522, NM_178227, NM_001359700
Synonyms	1110001K16Rik; 4833414B02Rik; Scnb3
Summary	Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons (By similarity).[UniProtKB/Swiss-Prot Function]

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