Mouse Tpm4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tpm4
Locus ID	326618
Kit Components	GA216612G1, Tpm4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216612G2, Tpm4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216612G3, Tpm4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001001491
Synonyms	2610528G24Rik; Tpm4.2; Tpm4.2cy
Summary	Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium.[UniProtKB/Swiss-Prot Function]

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